ABOUT ADVANCED PNET

PATIENTS TALK ABOUT THEIR AFINITOR THERAPY

PATIENTS TALK ABOUT THEIR AFINITOR THERAPY
CLICK HERE TO WATCH
 

HELPFUL RESOURCE FOR YOUR TREATMENT JOURNEY

AFINITOR PATIENT BROCHURE
 

LEARN MORE IN THE AFINITOR PATIENT BROCHURE

AFINITOR PATIENT BROCHURE
 

GET THE AFINITOR CO-PAY CARD

IMAGE: AFINITOR CO-PAY CARD
 

*Limitations apply. This offer is not valid under Medicare, Medicaid, or any other federal or state program. Novartis reserves the right to rescind, revoke, or amend this program without notice

 

Finding Help for Your Advanced Pancreatic Neuroendocrine Tumor Treatment Journey

Finding help for the journey ahead

Learning you have advanced PNET is very difficult. However, you can take control of your treatment, and you are not alone in your journey.

Learning as much as you can about advanced PNET will help you play a part in the important decisions you and your doctor will be making.

Helpful Links

National Organization for Rare Disorders The National Organization for Rare Disorders (NORD) is a unique federation of voluntary health organizations dedicated to helping people with rare "orphan" diseases and assisting the organizations that serve them. NORD is committed to the identification, treatment, and cure of rare disorders through programs of education, advocacy, research, and service.

Pancreatic Cancer Action Network The Pancreatic Cancer Action Network is a nationwide network of people. Its goal is to advance research, support patients, and create hope for those affected by pancreatic cancer. Its website provides useful tools and information related to pancreatic cancer, treatment options, patient stories, support resources, and more.

These resources refer to websites maintained by third parties over whom Novartis Pharmaceuticals Corporation has no control. As such, Novartis Pharmaceuticals Corporation makes no representation as to the accuracy, completeness, adequacy, or any other aspects of the information contained on such websites.

Additional Resources

Cancer resources

 

American Cancer Society (ACS) The American Cancer Society is a nationwide health organization dedicated to fighting cancer as a major health problem. Its website is a helpful resource for those newly diagnosed with cancer. It offers information about cancer, treating cancer, and support services.

Pancreatica The website for this nonprofit organization offers the latest news and information related to clinical trials and other responsible medical care in the treatment of pancreatic cancer. It includes a section dedicated to neuroendocrine tumors.

These resources refer to websites maintained by third parties over whom Novartis Pharmaceuticals Corporation has no control. As such, Novartis Pharmaceuticals Corporation makes no representation as to the accuracy, completeness, adequacy, or any other aspects of the information contained on such websites.

Support resources

 

Cancer Hope Network This not-for-profit organization provides free and confidential one-on-one support to people living with cancer and their family members.

Cancer Support Community This international nonprofit organization is dedicated to providing support, education, and hope to people affected by cancer.

National Coalition of Cancer Survivors (NCCS) A nationwide network of independent organizations and individuals who advocate for quality cancer care for all Americans and are dedicated to empowering cancer survivors.

These resources refer to websites maintained by third parties over whom Novartis Pharmaceuticals Corporation has no control. As such, Novartis Pharmaceuticals Corporation makes no representation as to the accuracy, completeness, adequacy, or any other aspects of the information contained on such websites.

Patient Access Services

 

Patient Advocate Foundation This foundation is dedicated to helping patients in medical debt crisis and advocates for patients with insurance access issues and job retention issues in the face of chronic, debilitating, and life-threatening illnesses.

CancerCare CancerCare is a nonprofit group. It offers free support services to patients and care partners affected by cancer. CancerCare programs provide counseling, education, and financial and practical help.

These resources refer to websites maintained by third parties over whom Novartis Pharmaceuticals Corporation has no control. As such, Novartis Pharmaceuticals Corporation makes no representation as to the accuracy, completeness, adequacy, or any other aspects of the information contained on such websites.

 

Important Safety Information

AFINITOR® (everolimus) Tablets can cause serious side effects, including lung or breathing problems, infections, and kidney failure, which can lead to death. Patients who take an angiotensin-converting enzyme (ACE) inhibitor medicine during treatment with AFINITOR are at a possible increased risk for a type of allergic reaction called angioedema. AFINITOR can cause incisions to heal slowly or not heal well. Mouth ulcers and mouth sores are common side effects, occurring in up to 86% of patients taking AFINITOR. AFINITOR can affect blood cell counts, kidney and liver function, and blood sugar and cholesterol levels. Regular blood tests should be performed before starting AFINITOR and as needed during treatment to check blood cell count, kidney and liver function, and blood sugar and cholesterol levels.

Please see additional

Important Safety Information.

 
 

Important Safety Information

Patients should not take AFINITOR if they are allergic to AFINITOR or to any of its ingredients. Patients should tell their health care provider before taking AFINITOR if they are allergic to sirolimus (Rapamune®) or temsirolimus (Torisel®).

AFINITOR can cause serious side effects that can even lead to death. If patients experience these side effects, they may need to stop taking AFINITOR for a while or use a lower dose. Patients should follow their health care provider's instructions. Serious side effects include:

Lung or Breathing Problems: In some patients, lung or breathing problems may be severe and can even lead to death. Patients should tell their health care provider right away if they have any of these symptoms: new or worsening cough, shortness of breath, chest pain, difficulty breathing, or wheezing.

Infections: AFINITOR may make patients more likely to develop an infection, such as pneumonia, or a bacterial, fungal, or viral infection. Viral infections may include reactivation of hepatitis B in people who have had hepatitis B in the past. In some people these infections may be severe and can even lead to death. Patients may need to be treated as soon as possible. Patients should tell their health care provider right away if they have a temperature of 100.5˚F or above, have chills, or do not feel well. Symptoms of hepatitis B or infection may include the following: fever, chills, skin rash, joint pain and inflammation, tiredness, loss of appetite, nausea, pale stools or dark urine, yellowing of the skin, or pain in the upper right side of the stomach.

Angioedema: Patients who take an angiotensin-converting enzyme (ACE) inhibitor medicine during treatment with AFINITOR are at a possible increased risk for a type of allergic reaction called angioedema. Talk with your health care provider before taking AFINITOR if you are not sure if you take an ACE inhibitor medicine. Get medical help right away if you have trouble breathing or develop swelling of your tongue, mouth, or throat during treatment with AFINITOR.

Kidney Failure: Patients taking AFINITOR may develop kidney failure. In some people this may be severe and can even lead to death. Patients should have tests to check their kidney function before and during their treatment with AFINITOR.

Delayed Wound Healing: AFINITOR can cause incisions to heal slowly or not heal well. Call your health care provider right away if your incision is red, warm, or painful; if you have blood, fluid, or pus in your incision; if your incision opens up; or if your incision swells.

Before taking AFINITOR, tell your health care provider about all your medical conditions, including if you:

Tell your health care provider about all of the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Using AFINITOR with certain other medicines can cause serious side effects. Keep a list of medicines you take and show it to your health care provider when you get a new medicine. Especially tell your health care provider if you take St John’s wort (Hypericum perforatum), medicines that weaken your immune system (your body’s ability to fight infections and other problems), or medicines for:

  • Fungal infections
  • Bacterial infections
  • Tuberculosis
  • Seizures
  • HIV-AIDS
  • Heart conditions or high blood pressure
 

If you are taking any medicines for the conditions listed above, your health care provider might need to prescribe a different medicine or your dose of AFINITOR may need to be changed. Tell your health care provider before you start taking any new medicine.

Common Side Effects: Common side effects include mouth ulcers. AFINITOR can cause mouth ulcers and sores. Tell your health care provider if you have pain, discomfort, or open sores in your mouth. Your health care provider may tell you to use a special mouthwash or gel that does not contain alcohol, hydrogen peroxide, iodine, or thyme.

Other common side effects include:

  • Rash, dry skin, and itching
  • Diarrhea
  • Infections
  • Feeling weak or tired
  • Swelling of arms, hands, feet, ankles, face, or other parts of the body
  • Stomach pain
  • Nausea
  • Fever
  • Loss of appetite, weight loss
  • Headache
  • Vomiting
  • Cough, shortness of breath
  • Nose bleed
  • Nail disorders
 

Tell your health care provider if you have any side effect that bothers you or does not go away.

These are not all the possible side effects of AFINITOR. For more information, ask your health care provider or pharmacist. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information for AFINITOR, including Patient Information.

The brands listed are the trademarks or register marks of their respective owners and are not trademarks or register marks of Novartis.

Indication

AFINITOR is a prescription medicine used to treat adults with a type of pancreatic cancer known as pancreatic neuroendocrine tumor (PNET) that has progressed and cannot be treated with surgery.

AFINITOR is not for use in people with carcinoid tumors that actively produce hormones.