About Afinitor for Advanced Renal Cell Carcinoma (RCC)

 

ABOUT aRCC

AFINITOR $25 CO-PAY CARD

IMAGE: AFINITOR Universal CO-PAY CARD
 
 
 

Resources for People With Advanced Kidney Cancer

Finding help for the journey ahead

Learning you have advanced kidney cancer is very difficult. However, you should remember that you are not alone and that you can take control of your treatment.

Learning as much as you can about kidney cancer will help you play a part in the important decisions you and your doctor will be making.

Sharing the information you learn with loved ones will help them better understand the journey too.

Help for your journey

The treatment of advanced kidney cancer is a journey. As you map your treatment journey, you may need some tools along the way to help keep track of important dates and appointments.

Advanced RCC Journey: A downloadable tool that has information about advanced kidney cancer and the treatment options available to you.

Download now:

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Talking to Others About Advanced Kidney Cancer

Communication is key

Learning that you have advanced kidney cancer can be a very difficult experience. However, it is important to remember that you are not alone in your treatment journey. Be sure to keep in mind that there is a community of individuals–health care professionals and caregivers, your family members, and close friends–who are available to provide you with medical and emotional support every step of the way. And, most importantly, there are things that you can do to take control of your treatment.

Finding the support you need

Learning as much as possible about your kidney cancer can help you play a role in the important decisions you and your doctor will be making.

If you have any questions or concerns about your disease or your treatment, be sure to talk to your doctor. Also remember to take advantage of your other support systems, such as:

  • Family and Friends: Knowing they support you and have an important role in your care can help your family become closer to you
  • Support Groups: Talking to other people with advanced kidney cancer can make you feel less alone. You may also learn more about what to expect along the way. In addition, you can meet people who want to share their insights and experiences. Ask your oncologist or clinic staff about local support groups

Remember, your journey with advanced kidney cancer is not one you are taking alone. If you have questions or concerns, or just need to talk, be sure to seek out the support you need, whether it be from your cancer care team, your family and friends, the members of a support group, or a counselor. Share your feelings with someone you trust. It can make a world of difference to talk about what you are going through.

Resources for Advanced Kidney Cancer

Explore these resources for more help along your treatment journey. This list includes Web links and toll-free phone numbers for a variety of organizations that provide information and support to people affected by cancer. The following organizations and websites are independently operated and not managed by Novartis Pharmaceuticals Corporation. Novartis assumes no responsibility for any information they may provide.

Kidney Cancer Support Resources

Kidney Cancer Association

www.kidneycancer.org

General Cancer Support Resources

American Cancer Society

www.cancer.org

CancerCare

www.cancercare.org

1-800-813-HOPE (1-800-813-4673)

Cancer Hope Network

www.cancerhopenetwork.org

Cancer Support Community

www.cancersupportcommunity.org

 

ADVANCED RENAL CELL CARCINOMA (aRCC)

AFINITOR® (everolimus) Tablets is a prescription medicine used to treat adults with advanced kidney cancer (renal cell carcinoma or RCC) when certain other medicines (ie, Sutent® [sunitinib] or Nexavar® [sorafenib]) have not worked.

Important Safety Information

AFINITOR can cause serious side effects, including lung or breathing problems, infections, and kidney failure, which can lead to death. Patients who take an angiotensin-converting enzyme (ACE) inhibitor medicine during treatment with AFINITOR are at a possible increased risk for a type of allergic reaction called angioedema. AFINITOR can cause incisions to heal slowly or not heal well. Mouth ulcers and mouth sores are common side effects, occurring in up to 78% of patients taking AFINITOR. AFINITOR can affect blood cell counts, kidney and liver function, and blood sugar and cholesterol levels. Regular blood tests should be performed before starting AFINITOR and as needed during treatment to check blood cell count, kidney and liver function, and blood sugar and cholesterol levels.

Please see additional

Important Safety Information.

Please see full Prescribing Information for AFINITOR, including Patient Information.

 
 

Important Safety Information

Patients should not take AFINITOR® (everolimus) Tablets if they are allergic to AFINITOR or to any of its ingredients. Patients should tell their health care provider before taking AFINITOR if they are allergic to sirolimus (Rapamune®) or temsirolimus (Torisel®).

AFINITOR can cause serious side effects that can even lead to death. If patients experience these side effects, they may need to stop taking AFINITOR for a while or use a lower dose. Patients should follow their health care provider's instructions. Serious side effects include:

Lung or Breathing Problems: In some patients, lung or breathing problems may be severe and can even lead to death. Patients should tell their health care provider right away if they have any of these symptoms: new or worsening cough, shortness of breath, chest pain, difficulty breathing, or wheezing.

Infections: AFINITOR may make patients more likely to develop an infection, such as pneumonia, or a bacterial, fungal, or viral infection. Viral infections may include reactivation of hepatitis B in people who have had hepatitis B in the past. In some people these infections may be severe and can even lead to death. Patients may need to be treated as soon as possible. Patients should tell their health care provider right away if they have a temperature of 100.5°F or above, have chills, or do not feel well. Symptoms of hepatitis B or infection may include the following: fever, chills, skin rash, joint pain and inflammation, tiredness, loss of appetite, nausea, pale stools or dark urine, yellowing of the skin, or pain in the upper right side of the stomach.

Angioedema: Patients who take an angiotensin-converting enzyme (ACE) inhibitor medicine during treatment with AFINITOR are at a possible increased risk for a type of allergic reaction called angioedema. Talk with your health care provider before taking AFINITOR if you are not sure if you take an ACE inhibitor medicine. Get medical help right away if you have trouble breathing or develop swelling of your tongue, mouth, or throat during treatment with AFINITOR.

Kidney Failure: Patients taking AFINITOR may develop kidney failure. In some people this may be severe and can even lead to death. Patients should have tests to check their kidney function before and during their treatment with AFINITOR.

Delayed Wound Healing: AFINITOR can cause incisions to heal slowly or not heal well. Call your health care provider right away if your incision is red, warm, or painful; if you have blood, fluid, or pus in your incision; if your incision opens up; or if your incision swells.

Before taking AFINITOR, tell your health care provider about all your medical conditions, including if you:

Tell your health care provider about all of the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Using AFINITOR with certain other medicines can cause serious side effects. Keep a list of medicines you take and show it to your health care provider when you get a new medicine. Especially tell your health care provider if you take St John's wort (Hypericum perforatum), medicines that weaken your immune system (your body's ability to fight infections and other problems), or medicines for:

  • Fungal infections
  • Bacterial infections
  • Tuberculosis
  • Seizures
  • HIV-AIDS
  • Heart conditions or high blood pressure
 

If you are taking any medicines for the conditions listed above, your health care provider might need to prescribe a different medicine or your dose of AFINITOR may need to be changed. Tell your health care provider before you start taking any new medicine.

Common Side Effects: Common side effects include mouth ulcers. AFINITOR can cause mouth ulcers and sores. Tell your health care provider if you have pain, discomfort, or open sores in your mouth. Your health care provider may tell you to use a special mouthwash or gel that does not contain alcohol, hydrogen peroxide, iodine, or thyme.

Other common side effects include:

  • Infections
  • Feeling weak or tired
  • Cough, shortness of breath
  • Diarrhea and constipation
  • Rash, dry skin, and itching
  • Nausea and vomiting
  • Fever
  • Loss of appetite, weight loss
  • Swelling of arms, hands, feet, ankles, face, or other parts of the body
  • Abnormal taste
  • Dry mouth
  • Inflammation of the lining of the digestive system
  • Headache
  • Nose bleeds
  • Pain in arms and legs, mouth and throat, back or joints
  • High blood glucose
  • High blood pressure
  • Difficulty sleeping
  • Hair loss
  • Muscle spasms
  • Feeling dizzy
  • Nail disorders
 

Other side effects that may occur with AFINITOR:

Tell your health care provider if you have any side effect that bothers you or does not go away.

These are not all the possible side effects of AFINITOR. For more information, ask your health care provider or pharmacist. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information for AFINITOR, including Patient Information.

The brands listed are the trademarks or register marks of their respective owners and are not trademarks or register marks of Novartis.

Indication

Advanced Renal Cell Carcinoma (RCC)

AFINITOR is a prescription medicine used to treat adults with advanced kidney cancer (renal cell carcinoma or RCC) when certain other medicines (ie, Sutent® [sunitinib] or Nexavar® [sorafenib]) have not worked.

The brands listed are the trademarks or registered trademarks of their respective owners and are not trademarks or register marks of Novartis.